Computational biology is everywhere. As biology has developed into a vast field over the last century, available data size increased both in terms of the analyzed samples and assessed biological characteristics. Translating these data into knowledge requires computational approaches. Whereas the spectrum of their applications is vast, ranging from species evolution to protein structures, from bacterial communities to human diseases, the underlying methods analyzing diverse data sets often share fundamental approaches, such as mathematical modeling, statistics, and AI. This symposium aims at bringing together computational biologists from different fields to showcase the transversal nature of their work with a strong emphasis on the applied methods. This shift of focus will bridge seemingly distant fields and provide a fertile ground for synergistic collaborations and unprecedented innovation.
Hosted by the Department of Computational Biology of the University of Lausanne, Switzerland, this meeting will welcome you in a friendly and relaxed environment on the shores of Lake Geneva, with plenty of opportunities for discussing your work and exchange ideas with new friends and colleagues. Join us in Lausanne!
Andrea Ganna
FIMM, University of Helsinki
MGH, Harvard Medical School
Anne-Florence
Bitbol
SV, EPFL
Helene Morlon
Ecole Normale Supérieure
Mo Lotfollahi
Wellcome Sanger Institute
Marianna Rapsomaniki
BDSC, CHUV
Michael P. Brenner
Harvard School of Engineering and Applied Sciences
Sonja
Lehtinen
DBC, University of Lausanne
Roser Vento-Tormo
Wellcome Sanger Institute
Blagoje Soskic
Human Technopole
Joana Pereira
VIB, KU Leuven
8:00 - 9:15 |
Open Registrations and Welcome Coffee
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9:15 - 9:30 |
Opening Remarks
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9:30 - 10:15 |
Andrea Ganna - Keynote 1 University of Helsinki, MGH - Harvard Medical School
Sex-related signatures in the plasma proteome not attributable to XX and XY chromosomes and their impact on health and disease
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10:15 - 10:30 |
Axel Schmidt - Short Talk University of Bonn
Host control of Epstein-Barr virus (EBV) latent infection
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10:30 - 10:45 |
Chiara Auwerx - Short Talk DBC - University of Lausanne / Harvard
Assortative mating exacerbates the impact of rare pathogenic CNVs
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10:45 - 11:00 |
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11:00 - 11:30 |
Coffee Break
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11:30 - 12:00 |
Anne-Florence Bitbol - Invited Speaker EPFL
Predicting protein-protein interactions using protein language models
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12:00 - 12:30 |
Helene Morlon - Invited Speaker Ecole Normale Superiore, Paris
Negative global-scale association between genetic diversity and speciation rates
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12:30 - 14:00 |
Lunch Break on Site & Poster Session
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14:00 - 14:30 |
Mo Lotfollahi - Invited Speaker Wellcome Sanger Institute, Cambridge, UK
Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning
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14:30 - 14:45 |
Deepak Yadav - Short Talk DBC - University of Lausanne
Training graph neural network to classify SNARE proteins structures
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14:45 - 15:00 |
Dennis Bontempi - Short Talk DBC - University of Lausanne
Genetic and Prognostic Insights from Deep Learning Segmentation of Carotid Lumen Diameter
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15:00 - 15:20 |
Debora Sesia; Aurora Savino - Short Talk DBC - University of Lausanne / Human Technopole
Functional Assessment of Variants of Unknown Significance through the Cancer Dependency Map
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15:20 - 15:45 |
Coffee Break
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15:45 - 16:15 |
Marianna Rapsomaniki - Invited Speaker CHUV
Matching single cells across modalities with contrastive learning and optimal transport.
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16:15 - 16:30 |
Vanessa Vermeirssen - Short Talk Ghent University
Modeling disease metabolism from multi-omics data
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16:30 - 16:45 |
Daan de Groot - Short Talk University of Basel
Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data
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16:45 - 17:00 |
Davide Bozzi - Short Talk DBC - University of Lausanne
A 5,500-year-old Treponema pallidum genome from Sabana de Bogotá, Colombia
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17:00 - 17:15 |
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17:30 - 19:00 |
Poster Session and Apero
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19:00 - 22:00 |
Social Dinner
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9:15 - 10:00 |
Michael P. Brenner - Keynote 2 - Alma Dal Co Memorial Lecture Harvard School of Engineering and Applied Sciences
Revealing Lineage-Related Signals in Single-Cell Gene Expression Using Random Matrix Theory
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10:00 - 10:15 |
Thibault Latrille - Short Talk DBC - University of Lausanne
Between and within species variation to detect selection on gene expression level in mammals
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10:15 - 10:30 |
Gábor Holló - Short Talk DEE - University of Lausanne
Turing Instability and Pattern Formation in Microbial Consortia
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10:30 - 10:45 |
Marina Papadopoulou - Short Talk University of Tuscia
Data-inspired simulations of collective escape: the case of starling murmurations
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10:45 - 11:15 |
Coffee Break
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11:15 - 11:45 |
Sonja Lehtinen - Invited Speaker DBC
Antibiotic resistance dynamics
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11:45 - 12:00 |
Athina Gavriilidou - Short Talk DBC - University of Lausanne
Cracking the animal venom code using phylogenetic big data
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12:00 - 12:15 |
Matthew Boyton - Short Talk Heritability-informed drug repurposing across immune mediated traits
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12:15 - 12:30 |
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12:30 - 14:00 |
Lunch Break on Site & Poster Session
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14:00 - 14:30 |
Roser Vento-Tormo - Invited Speaker Wellcome Sanger Institute, Cambridge, UK
Gene regulation of human cell systems
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14:30 - 14:45 |
Robin Journot - Short Talk Institut Curie
Conserved molecular mechanisms and functional diversification in multilayered epithelia
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14:45 - 15:00 |
Bethany Voller - Short Talk University of Exeter
Using genetics to understand the shared mechanisms of hypertension and type 2 diabetes after accounting for obesity and cholesterol
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15:00 - 15:15 |
Pierre Bost - Short Talk Next-generation statistical framework for next-generation spatial transcriptomics data
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15:15 - 15:45 |
Coffee Break
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15:45 - 16:15 |
Joana Pereira - Invited Speaker VIB, KU Leuven
Mapping the entire protein universe
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16:15 - 16:30 |
Julian van Gerwen - Short Talk The functional landscape of the human ubiquitinome
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16:30 - 16:45 |
Mehdi Mirzaie - Short Talk A Novel Protein Representation Based on of Pairwise Interaction Energies
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16:45 - 17:15 |
Blagoje Soskic - Invited Speaker Human Technopole, IT
Genome wide association studies (GWAS) in immune-mediated diseases
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17:30 - 18:00 |
Concluding Remarks and Poster Prize
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18:00 - 19:00 |
Apero
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Starling Hotel Lausanne ★★★★
Rte Cantonale 31, CH-1025 Saint-Sulpice
The nearest international airport is Geneva Airport, located 60 km from Lausanne. Geneva Airport is serviced by numerous airline companies providing connections with European cities like Paris, London, and Frankfurt, as well as a few non-European destinations. To get from Geneva Airport to Lausanne, attendees can use the train from Geneva Airport to Lausanne train station (~45 minutes) Alternatively, Lausanne can be reached by car from Geneva Airport in approximately 45 minutes
Lausanne is well connected by train to all major cities in Switzerland. The main train station is located in the city center and offers frequent connections to cities like Zurich, Bern, and Geneva. Please see Swiss Railways website to access train schedules.
A large number of hotels located right in the city centre, not far from the symposium venue, close to Lake Geneva:
Address: Rue du Petit-Chêne 34, 1003 Lausanne.
Address: Avenue du Rond-Point 9, 1006 Lausanne.
Address: Rue Grand-Saint-Jean 19, 1003 Lausanne.
Address: Av. Sainte-Luce 1, 1003 Lausanne.
Address: Chem. du Bois-de-Vaux 36, 1007 Lausanne.
Address: Rue Pré-du-Marché 42, 1004 Lausanne.
The University of Lausanne (UNIL) is nestled along the picturesque shores of Lake Geneva in Switzerland. The campus is a vibrant hub of academic and social activity, surrounded by lush greenery and stunning views of the lake and mountains. With modern facilities, including libraries, sports centers, and cafes, students have everything they need within walking distance. The nearby city of Lausanne offers a rich cultural experience with museums, theaters, and a lively nightlife. Whether you're attending a lecture or enjoying a leisurely stroll by the lake, the UNIL campus provides an inspiring and welcoming environment for all.
Zoltán Kutalik
Giovanni Ciriello
Michelle N'Cho